BDBM50334905 CHEMBL1643262::ethyl 4-(3-(1-methyl-1H-pyrazol-4-yl)-5-(piperidin-3-yl)pyrazolo[1,5-a]pyrimidin-7-ylamino)benzoate

SMILES CCOC(=O)c1ccc(Nc2cc(nc3c(cnn23)-c2cnn(C)c2)C2CCCNC2)cc1

InChI Key InChIKey=VISPRZALIOPZFK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50334905   

TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50334905(ethyl 4-(3-(1-methyl-1H-pyrazol-4-yl)-5-(piperidin...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CDK2/cyclin AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50334905(ethyl 4-(3-(1-methyl-1H-pyrazol-4-yl)-5-(piperidin...)
Affinity DataIC50: 51nMAssay Description:Inhibition of recombinant His-CHK1 expressed in baculovirus after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed