BDBM50334440 (R)-7-(quinuclidin-3-yl)-7,8-dihydropyrazolo[3,4,5-de]isoquinolin-6(2H)-one::CHEMBL1643881::US8501729, 16

SMILES O=c1n(cc2[nH][nH]c3cccc1c23)[C@H]1CN2CCC1CC2

InChI Key InChIKey=ATTAPIQZQXPNMZ-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50334440   

Target5-hydroxytryptamine receptor 3A(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50334440(US8501729, 16 | CHEMBL1643881 | (R)-7-(quinuclidin...)
Affinity DataEC50:  14.5nMAssay Description:Partial agonist activity at human 5HT3A receptor expressed in HEK293 cells assessed as effect on serotonin-induced responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50334440(US8501729, 16 | CHEMBL1643881 | (R)-7-(quinuclidin...)
Affinity DataKi:  4.40nMAssay Description:Binding affinity to human 5HT3A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50334440(US8501729, 16 | CHEMBL1643881 | (R)-7-(quinuclidin...)
Affinity DataKi:  5nMpH: 7.5Assay Description:The relative affinity of the various compounds for the human 5-HT3 receptor was measured in a radioligand binding assay, using a scintillation proxim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2013
Entry Details
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