BDBM50333979 2-(3-(2-(2-(2,4-dichlorophenyl)-5-isopropyloxazol-4-yl)ethyl)-5-methylbenzo[d]isoxazol-6-yloxy)acetic acid::CHEMBL1644614

SMILES CC(C)c1oc(nc1CCc1noc2cc(OCC(O)=O)c(C)cc12)-c1ccc(Cl)cc1Cl

InChI Key InChIKey=JDTVEJCQPMSSOE-UHFFFAOYSA-N

Data  9 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50333979   

TargetPeroxisome proliferator-activated receptor alpha(Human)
Nippon Chemiphar

Curated by ChEMBL
LigandPNGBDBM50333979(2-(3-(2-(2-(2,4-dichlorophenyl)-5-isopropyloxazol-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Transactivation of Gal4-fused human PPARalpha DNA binding domain expressed in african green monkey CV1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Nippon Chemiphar

Curated by ChEMBL
LigandPNGBDBM50333979(2-(3-(2-(2-(2,4-dichlorophenyl)-5-isopropyloxazol-...)
Affinity DataEC50:  1.00E+4nMAssay Description:Transactivation of full length human PPARgamma expressed in african green monkey CV1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Nippon Chemiphar

Curated by ChEMBL
LigandPNGBDBM50333979(2-(3-(2-(2-(2,4-dichlorophenyl)-5-isopropyloxazol-...)
Affinity DataEC50:  1.00E+4nMAssay Description:Transactivation of full length human PPARalpha expressed in african green monkey CV1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Nippon Chemiphar

Curated by ChEMBL
LigandPNGBDBM50333979(2-(3-(2-(2-(2,4-dichlorophenyl)-5-isopropyloxazol-...)
Affinity DataEC50:  25nMAssay Description:Transactivation of Gal4-fused human PPARdelta DNA binding domain expressed in african green monkey CV1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Nippon Chemiphar

Curated by ChEMBL
LigandPNGBDBM50333979(2-(3-(2-(2-(2,4-dichlorophenyl)-5-isopropyloxazol-...)
Affinity DataEC50:  4.5nMAssay Description:Transactivation of full length human PPARdelta expressed in african green monkey CV1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Nippon Chemiphar

Curated by ChEMBL
LigandPNGBDBM50333979(2-(3-(2-(2-(2,4-dichlorophenyl)-5-isopropyloxazol-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Transactivation of Gal4-fused human PPARgamma DNA binding domain expressed in african green monkey CV1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Nippon Chemiphar

Curated by ChEMBL
LigandPNGBDBM50333979(2-(3-(2-(2-(2,4-dichlorophenyl)-5-isopropyloxazol-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human PPARalpha-LBD expressed in CV1 cells co-transfected with Gal4 after 40 hrs by luciferase based transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Nippon Chemiphar

Curated by ChEMBL
LigandPNGBDBM50333979(2-(3-(2-(2-(2,4-dichlorophenyl)-5-isopropyloxazol-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human PPARgamma-LBD expressed in CV1 cells co-transfected with Gal4 after 40 hrs by luciferase based transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Nippon Chemiphar

Curated by ChEMBL
LigandPNGBDBM50333979(2-(3-(2-(2-(2,4-dichlorophenyl)-5-isopropyloxazol-...)
Affinity DataEC50:  25nMAssay Description:Agonist activity at human PPARdelta-LBD expressed in CV1 cells co-transfected with Gal4 after 40 hrs by luciferase based transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed