BDBM50332525 CHEMBL1630488::N-(4-methoxyphenyl)-5-(4-nitrophenyl)-1,3,4-oxadiazol-2-amine

SMILES COc1ccc(Nc2nnc(o2)-c2ccc(cc2)[N+]([O-])=O)cc1

InChI Key InChIKey=UFGGHUIRJJQBNM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50332525   

TargetGlycogen synthase kinase-3 beta(Human)
University of Louisiana At Monroe

Curated by ChEMBL
LigandPNGBDBM50332525(N-(4-methoxyphenyl)-5-(4-nitrophenyl)-1,3,4-oxadia...)
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant GSK3-beta Z'-LYTE kinase assay kit methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50332525(N-(4-methoxyphenyl)-5-(4-nitrophenyl)-1,3,4-oxadia...)
Affinity DataIC50: 6.41E+4nMAssay Description:Inhibition of PD-1/PD-L1 (unknown origin) interaction pre-incubated for 15 mins and measured after 90 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed