BDBM50331885 6-chloro-8-(4-sulfamoylphenyl)-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid::CHEMBL1290433

SMILES NS(=O)(=O)c1ccc(cc1)-c1cc(Cl)cc2C=C(C(Oc12)C(F)(F)F)C(O)=O

InChI Key InChIKey=JGPRUEXSKNEPHR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50331885   

TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331885(6-chloro-8-(4-sulfamoylphenyl)-2-(trifluoromethyl)...)
Affinity DataIC50: 9.14E+4nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331885(6-chloro-8-(4-sulfamoylphenyl)-2-(trifluoromethyl)...)
Affinity DataIC50: 1.74E+3nMAssay Description:Inhibition of human COX-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331885(6-chloro-8-(4-sulfamoylphenyl)-2-(trifluoromethyl)...)
Affinity DataIC50: 758nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331885(6-chloro-8-(4-sulfamoylphenyl)-2-(trifluoromethyl)...)
Affinity DataIC50: 760nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed