BDBM50331770 1-(4'-((S)-1-((S)-1-((S)-1-cyano-2-phenylethylamino)-4-fluoro-4-methyl-1-oxopentan-2-ylamino)-2,2,2-trifluoroethyl)biphenyl-4-yl)cyclopropanecarboxamide::CHEMBL1288525

SMILES CC(C)(F)C[C@H](N[C@@H](c1ccc(cc1)-c1ccc(cc1)C1(CC1)C(N)=O)C(F)(F)F)C(=O)N[C@@H](Cc1ccccc1)C#N

InChI Key InChIKey=ZUKNWGIRWRHHPH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50331770   

TargetCathepsin F(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331770(1-(4'-((S)-1-((S)-1-((S)-1-cyano-2-phenylethylamin...)
Affinity DataIC50: 37nMAssay Description:Inhibition of human Cat F expressed in rabbit HIG82 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331770(1-(4'-((S)-1-((S)-1-((S)-1-cyano-2-phenylethylamin...)
Affinity DataIC50: 426nMAssay Description:Inhibition of human Cat LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331770(1-(4'-((S)-1-((S)-1-((S)-1-cyano-2-phenylethylamin...)
Affinity DataIC50: 3nMAssay Description:Inhibition of Trypanosoma cruzi CruzipainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetCathepsin B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331770(1-(4'-((S)-1-((S)-1-((S)-1-cyano-2-phenylethylamin...)
Affinity DataIC50: 27nMAssay Description:Inhibition of human Cat B in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed