BDBM50331755 CHEMBL1288517::methyl 3,5-bis(trifluoromethyl)benzyl((4'-fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)biphenyl-2-yl)methyl)carbamate

SMILES COC(=O)N(Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F)Cc1cc(ccc1-c1cc(C(C)C)c(F)cc1OC)C(F)(F)F

InChI Key InChIKey=FGKHLSWPVWXFAR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50331755   

TargetCholesteryl ester transfer protein(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50331755(methyl 3,5-bis(trifluoromethyl)benzyl((4'-fluoro-5...)
Affinity DataIC50: 117nMAssay Description:Inhibition of CETP-mediated neutral lipid transfer by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50331755(methyl 3,5-bis(trifluoromethyl)benzyl((4'-fluoro-5...)
Affinity DataIC50: 117nMAssay Description:Inhibition of human recombinant CETP-mediated cholesteryl ester transfer activity after 1 hr by fluorescent cholesteryl esters transfer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed