BDBM50331679 (2R,3R,4S)-3-acetamido-2-((1R,2R)-1,2-dihydroxy-3-(4-(2-hydroxyethyl)-1H-1,2,3-triazol-1-yl)propyl)-4-hydroxy-3,4-dihydro-2H-pyran-6-carboxylate::CHEMBL1289754

SMILES CC(=O)N[C@@H]1[C@@H](O)C=C(O[C@H]1[C@H](O)[C@H](O)Cn1cc(CCO)nn1)C(O)=O

InChI Key InChIKey=LOBCLUJEPFNFNV-UHFFFAOYSA-N

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50331679   

TargetSialidase-4(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50331679((2R,3R,4S)-3-acetamido-2-((1R,2R)-1,2-dihydroxy-3-...)
Affinity DataIC50: 810nMAssay Description:Inhibition of human NEU4 using 4-MU-NANA as substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence plate...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSialidase-3(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50331679((2R,3R,4S)-3-acetamido-2-((1R,2R)-1,2-dihydroxy-3-...)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of human NEU3 using 4-MU-NANA as substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence plate...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSialidase-2(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50331679((2R,3R,4S)-3-acetamido-2-((1R,2R)-1,2-dihydroxy-3-...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human NEU2 using 4-MU-NANA as substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence plate...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSialidase-1(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50331679((2R,3R,4S)-3-acetamido-2-((1R,2R)-1,2-dihydroxy-3-...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human NEU1 using 4-MU-NANA as substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence plate...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSialidase-3(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50331679((2R,3R,4S)-3-acetamido-2-((1R,2R)-1,2-dihydroxy-3-...)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of human neuraminidase 3 assessed as inhibition of 4-methylumbelliferyl-alpha-D-glucopyranoside hydrolysis by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSialidase-4(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50331679((2R,3R,4S)-3-acetamido-2-((1R,2R)-1,2-dihydroxy-3-...)
Affinity DataIC50: 810nMAssay Description:Inhibition of NEU4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSialidase-4(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50331679((2R,3R,4S)-3-acetamido-2-((1R,2R)-1,2-dihydroxy-3-...)
Affinity DataKi:  60nMAssay Description:Inhibition of human NEU4 using 4-MU-NANA as substrate measured every 30 seconds for 60 mins by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed