BDBM50331185 4-(benzyloxy)-1-(9-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-7-yl)pyridin-2(1H)-one::CHEMBL1289395

SMILES Cn1c2CNCCc2c2ccc(cc12)-n1ccc(OCc2ccccc2)cc1=O

InChI Key InChIKey=ZXGHIZDLSIWWGJ-UHFFFAOYSA-N

Data  1 KI  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50331185   

TargetCytochrome P450 2D6(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50331185(4-(benzyloxy)-1-(9-methyl-2,3,4,9-tetrahydro-1H-py...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50331185(4-(benzyloxy)-1-(9-methyl-2,3,4,9-tetrahydro-1H-py...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetCytochrome P450 2B6(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50331185(4-(benzyloxy)-1-(9-methyl-2,3,4,9-tetrahydro-1H-py...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2B6More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50331185(4-(benzyloxy)-1-(9-methyl-2,3,4,9-tetrahydro-1H-py...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
LigandPNGBDBM50331185(4-(benzyloxy)-1-(9-methyl-2,3,4,9-tetrahydro-1H-py...)
Affinity DataIC50: 14.4nMAssay Description:Antagonist activity at MCH-1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50331185(4-(benzyloxy)-1-(9-methyl-2,3,4,9-tetrahydro-1H-py...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50331185(4-(benzyloxy)-1-(9-methyl-2,3,4,9-tetrahydro-1H-py...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
LigandPNGBDBM50331185(4-(benzyloxy)-1-(9-methyl-2,3,4,9-tetrahydro-1H-py...)
Affinity DataKi:  4.90nMAssay Description:Displacement of [3H]4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)pyridin-2(1H)-one from MCH-1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed