BDBM50331109 6-(9H-carbazol-9-yl)-N-hydroxyhexanamide::CHEMBL1290142::US8748451, 1

SMILES ONC(=O)CCCCCn1c2ccccc2c2ccccc12

InChI Key InChIKey=SOMDVJCUFVPZKM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50331109   

TargetHistone deacetylase 1(Human)
University of Illinois

US Patent
LigandPNGBDBM50331109(CHEMBL1290142 | US8748451, 1 | 6-(9H-carbazol-9-yl...)
Affinity DataIC50: 1.40E+4nMpH: 8.0 T: 2°CAssay Description:HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
University of Illinois

US Patent
LigandPNGBDBM50331109(CHEMBL1290142 | US8748451, 1 | 6-(9H-carbazol-9-yl...)
Affinity DataIC50: 62nMpH: 8.0 T: 2°CAssay Description:HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
University of Illinois

US Patent
LigandPNGBDBM50331109(CHEMBL1290142 | US8748451, 1 | 6-(9H-carbazol-9-yl...)
Affinity DataIC50: 3.07E+3nMAssay Description:Inhibition of recombinant human HDAC1 using Ac-RHKK(Ac)-ACC as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Illinois

US Patent
LigandPNGBDBM50331109(CHEMBL1290142 | US8748451, 1 | 6-(9H-carbazol-9-yl...)
Affinity DataIC50: 41nMAssay Description:Inhibition of recombinant human HDAC6 using Ac-RHKK(Ac)-ACC as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed