BDBM50330853 CHEMBL66552::Sodium; 2-[4-(2-oxo-cyclopentylmethyl)-phenyl]-propionate; hydrate::loxoprofen sodium

SMILES CC(C([O-])=O)c1ccc(CC2CCCC2=O)cc1

InChI Key InChIKey=YMBXTVYHTMGZDW-UHFFFAOYSA-M

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50330853   

TargetProstaglandin G/H synthase 1(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50330853(Sodium; 2-[4-(2-oxo-cyclopentylmethyl)-phenyl]-pro...)
Affinity DataIC50: 2.35E+4nMAssay Description:Inhibition of COX1 in human whole blood assessed as TXB2 biosynthesis after 24 hrs by EIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50330853(Sodium; 2-[4-(2-oxo-cyclopentylmethyl)-phenyl]-pro...)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of human whole blood COX-1 assessed as production of TXB2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50330853(Sodium; 2-[4-(2-oxo-cyclopentylmethyl)-phenyl]-pro...)
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of COX2 in human whole blood assessed as PGE2 biosynthesis after 24 hrs by EIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50330853(Sodium; 2-[4-(2-oxo-cyclopentylmethyl)-phenyl]-pro...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human whole blood COX-2 assessed as production of PGE2 after 24 hrs by EIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed