BDBM50330563 CHEMBL1277294::N-(4-Nitrobenzyl)-4-furan-2-methyl-1,4-dihydrobenzo[4,5]imidazo[1,2-a]pyrimidine-3-carboxamide

SMILES CC1=Nc2nc3ccccc3n2C(C1C(=O)Nc1ccc(cc1)[N+]([O-])=O)c1ccco1

InChI Key InChIKey=PPOWHZRYXUCWMA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50330563   

TargetAurora kinase A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330563(N-(4-Nitrobenzyl)-4-furan-2-methyl-1,4-dihydrobenz...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human purified recombinant aurora-A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50330563(N-(4-Nitrobenzyl)-4-furan-2-methyl-1,4-dihydrobenz...)
Affinity DataIC50: 2.09E+4nMAssay Description:Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed