BDBM50330440 3-Amino-2-[3-(4-quinolin-2-ylpiperazin-1-yl)propylthio]-5,6,7,8-tetrahydro-3H-quinazolin-4-one::CHEMBL1277281

SMILES Nn1c(SCCCN2CCN(CC2)c2ccc3ccccc3n2)nc2CCCCc2c1=O

InChI Key InChIKey=OJNSMLDRVFFVJN-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50330440   

Target5-hydroxytryptamine receptor 1A(Human)
Aska Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50330440(3-Amino-2-[3-(4-quinolin-2-ylpiperazin-1-yl)propyl...)
Affinity DataIC50: 5.60nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Aska Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50330440(3-Amino-2-[3-(4-quinolin-2-ylpiperazin-1-yl)propyl...)
Affinity DataEC50:  182nMAssay Description:Agonist activity at human cloned 5HT1A receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding after 30 mins by liquid scin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Aska Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50330440(3-Amino-2-[3-(4-quinolin-2-ylpiperazin-1-yl)propyl...)
Affinity DataIC50: 63.8nMAssay Description:Displacement of [3H]BRL-43694 from human 5HT3 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed