BDBM50330241 (E)-4-(Dimethylamino)-1-(4-[(1R)-1-phenylethyl]amino-5,6,7,8-tetrahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-7-yl)-2-buten-1-one::CHEMBL1271561::US8524722, 23

SMILES C[C@@H](Nc1ncnc2sc3CN(CCc3c12)C(=O)\C=C\CN(C)C)c1ccccc1

InChI Key InChIKey=BVGZQNBERZRYJK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50330241   

TargetEpidermal growth factor receptor(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM50330241(CHEMBL1271561 | US8524722, 23 | (E)-4-(Dimethylami...)
Affinity DataIC50: 4.60nMpH: 7.0 T: 2°CAssay Description:EGFR inhibitory activity of compounds of the present invention is quantified employing the EGFR HTRF assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2013
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM50330241(CHEMBL1271561 | US8524722, 23 | (E)-4-(Dimethylami...)
Affinity DataIC50: 12nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed