BDBM50329609 5-(3-(biphenyl-3-yl)prop-1-ynyl)-6-ethylpyrimidine-2,4-diamine::CHEMBL1270439
SMILES CCc1nc(N)nc(N)c1C#CCc1cccc(c1)-c1ccccc1
InChI Key InChIKey=DGJGWMFHVPDAKM-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50329609
Affinity DataIC50: 28nMAssay Description:Heterocyclic analogs of propargyl-linked inhibitors of the third generation analogs were evaluated in enzyme inhibition assays, assessed for S. aureu...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Streptococcus pyogenes (Firmicutes))
University of Connecticut
US Patent
University of Connecticut
US Patent
Affinity DataIC50: 26nMAssay Description:Heterocyclic analogs of propargyl-linked inhibitors of the third generation analogs were evaluated in enzyme inhibition assays, assessed for S. aureu...More data for this Ligand-Target Pair
Affinity DataIC50: 290nMAssay Description:Heterocyclic analogs of propargyl-linked inhibitors of the third generation analogs were evaluated in enzyme inhibition assays, assessed for S. aureu...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of wild type Bacillus anthracis recombinant DHFRMore data for this Ligand-Target Pair
Affinity DataKi: 370nMAssay Description:Inhibition of wild type Bacillus anthracis recombinant DHFRMore data for this Ligand-Target Pair