BDBM50329533 (R,E)-2-amino-4-(3-(4,4-difluorobut-1-enyl)phenyl)-4-(4-(difluoromethoxy)phenyl)-1-methyl-1H-imidazol-5(4H)-one::CHEMBL1270433
SMILES CN1C(N)=N[C@](C1=O)(c1ccc(OC(F)F)cc1)c1cccc(\C=C\CC(F)F)c1
InChI Key InChIKey=VSAWCPRVIUYQEL-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50329533
Affinity DataIC50: 30nMAssay Description:Inhibition of human BACE1 by FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 120nMAssay Description:Inhibition of human recombinant BACE1 expressed in CHO cells assessed as reduction in amyloid beta level by sandwich ELISAMore data for this Ligand-Target Pair