BDBM50329430 5-(2-Amino-pyrimidin-4-yl)-2-thiophen-3-yl-1H-pyrrole-3-carboxamide::CHEMBL1269729::US9670191, G1

SMILES NC(=O)c1cc([nH]c1-c1ccsc1)-c1ccnc(N)n1

InChI Key InChIKey=GIEWZQNAONSKKX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50329430   

TargetCell division cycle 7-related protein kinase(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50329430(5-(2-Amino-pyrimidin-4-yl)-2-thiophen-3-yl-1H-pyrr...)
Affinity DataIC50: 39nMAssay Description:Inhibition of Cdc7More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
LigandPNGBDBM50329430(5-(2-Amino-pyrimidin-4-yl)-2-thiophen-3-yl-1H-pyrr...)
Affinity DataIC50: 100nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
Go to US Patent