BDBM50329207 5-(4-chlorophenyl)-N-((2-chloropyridin-3-yl)methyl)nicotinamide::CHEMBL1270100

SMILES Clc1ccc(cc1)-c1cncc(c1)C(=O)NCc1cccnc1Cl

InChI Key InChIKey=JJLXCDLYMWHMIF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50329207   

TargetSodium channel protein type 10 subunit alpha(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329207(5-(4-chlorophenyl)-N-((2-chloropyridin-3-yl)methyl...)
Affinity DataIC50: 560nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetSodium channel protein type 2 subunit alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329207(5-(4-chlorophenyl)-N-((2-chloropyridin-3-yl)methyl...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human NaV1.2 by electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetSodium channel protein type 10 subunit alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329207(5-(4-chlorophenyl)-N-((2-chloropyridin-3-yl)methyl...)
Affinity DataIC50: 140nMAssay Description:Inhibition of human NaV1.8 by electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetSodium channel protein type 10 subunit alpha(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329207(5-(4-chlorophenyl)-N-((2-chloropyridin-3-yl)methyl...)
Affinity DataIC50: 680nMAssay Description:Inhibition of mouse NaV1.8 by electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed