BDBM50328744 7-hydroxy-8-((2-methoxy-5-(vinylsulfonyl)phenyl)diazenyl)naphthalene-1,3-disulfonate::CHEMBL1271164

SMILES COc1ccc(cc1N=Nc1c(O)ccc2cc(cc(c12)S(O)(=O)=O)S(O)(=O)=O)S(=O)(=O)C=C

InChI Key InChIKey=YXZOMAMIMXZGQS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50328744   

TargetProtein arginine N-methyltransferase 1 [11-371](Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50328744(7-hydroxy-8-((2-methoxy-5-(vinylsulfonyl)phenyl)di...)
Affinity DataIC50: 4.31E+4nMAssay Description:Inhibition of His6x-tagged PRMT1-mediated protein arginine methylation expressed in Escherichia coli BL21 (DE3) using H4(1-20) and [14C]-SAM by scint...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50328744(7-hydroxy-8-((2-methoxy-5-(vinylsulfonyl)phenyl)di...)
Affinity DataIC50: 1.08E+5nMAssay Description:Inhibition of His6x-tagged PRMT1-mediated protein arginine methylation expressed in Escherichia coli BL21 (DE3) using GAR R4 peptide and [14C]-AdoMet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50328744(7-hydroxy-8-((2-methoxy-5-(vinylsulfonyl)phenyl)di...)
Affinity DataIC50: 5.05E+4nMAssay Description:Inhibition of human GST-tagged PRMT1-mediated arginine methylation expressed in Escherichia coli BL21 (DE3) using H4(1-20) and [14C]-AdoMet by scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed