BDBM50328637 CHEMBL1259241::benzo[b]thiophen-3-yl(4-fluoro-4-(((5-methylpyridin-2-yl)methylamino)methyl)piperidin-1-yl)methanone

SMILES Cc1ccc(CNCC2(F)CCN(CC2)C(=O)c2csc3ccccc23)nc1

InChI Key InChIKey=TXTILBTZVJQWSG-UHFFFAOYSA-N

Data  5 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50328637   

Target5-hydroxytryptamine receptor 1A(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50328637(benzo[b]thiophen-3-yl(4-fluoro-4-(((5-methylpyridi...)
Affinity DataEC50:  10nMAssay Description:Intrinsic activity at human 5-HT1A receptor expressed in CHO cells assessed as increase of serotonin-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50328637(benzo[b]thiophen-3-yl(4-fluoro-4-(((5-methylpyridi...)
Affinity DataKi:  8.70E+3nMAssay Description:Displacement of [3H]Spiperone from human dopamine D3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50328637(benzo[b]thiophen-3-yl(4-fluoro-4-(((5-methylpyridi...)
Affinity DataKi:  2.00E+4nMAssay Description:Displacement of [3H]Spiperone from human dopamine D2 long receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Pig)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50328637(benzo[b]thiophen-3-yl(4-fluoro-4-(((5-methylpyridi...)
Affinity DataKi:  2.20E+4nMAssay Description:Displacement of [3H]Ketanserin from 5-HT2 receptor in pig cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Pig)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50328637(benzo[b]thiophen-3-yl(4-fluoro-4-(((5-methylpyridi...)
Affinity DataKi:  4.50E+4nMAssay Description:Displacement of [3H]SCH23390 from dopamine D1 receptor in pig cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50328637(benzo[b]thiophen-3-yl(4-fluoro-4-(((5-methylpyridi...)
Affinity DataKi:  5.40E+4nMAssay Description:Displacement of [3H]Spiperone from human dopamine D2 short receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed