BDBM50328536 5,6-Dichloro-2-[(2S)-1-(2-methylalanyl-O-methyl-L-tyrosyl)-azetidin-2-yl]-1H-benzimidazole::CHEMBL1259134

SMILES COc1ccc(C[C@H](NC(=O)C(C)(C)N)C(=O)N2CC[C@H]2c2nc3cc(Cl)c(Cl)cc3[nH]2)cc1

InChI Key InChIKey=QKKNJLFVWMLFBP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50328536   

TargetLysosomal Pro-X carboxypeptidase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50328536(5,6-Dichloro-2-[(2S)-1-(2-methylalanyl-O-methyl-L-...)
Affinity DataIC50: 829nMAssay Description:Inhibition of human PrCP by FRET in presence of 1% mouse serum albuminMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysosomal Pro-X carboxypeptidase(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50328536(5,6-Dichloro-2-[(2S)-1-(2-methylalanyl-O-methyl-L-...)
Affinity DataIC50: 251nMAssay Description:Inhibition of mouse PrCP by FRETMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysosomal Pro-X carboxypeptidase(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50328536(5,6-Dichloro-2-[(2S)-1-(2-methylalanyl-O-methyl-L-...)
Affinity DataIC50: 3.32E+3nMAssay Description:Inhibition of mouse PrCP by FRET in presence of 1% mouse serum albuminMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysosomal Pro-X carboxypeptidase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50328536(5,6-Dichloro-2-[(2S)-1-(2-methylalanyl-O-methyl-L-...)
Affinity DataIC50: 9nMAssay Description:Inhibition of human PrCP by FRETMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed