BDBM50328531 3-(Biphenyl-4-yl)-1-{2-[5-(3-fluorophenyl)-1H-imidazol-2-yl]-pyrrolidin-1-yl}-2,2-dimethylpropan-1-one::CHEMBL1259069

SMILES CC(C)(Cc1ccc(cc1)-c1ccccc1)C(=O)N1CCC[C@H]1c1nc(c[nH]1)-c1cccc(F)c1

InChI Key InChIKey=RMEWBPGDAAPWCD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50328531   

TargetLysosomal Pro-X carboxypeptidase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50328531(3-(Biphenyl-4-yl)-1-{2-[5-(3-fluorophenyl)-1H-imid...)
Affinity DataIC50: 1.46E+3nMAssay Description:Inhibition of human PrCP by FRET in presence of 1% mouse serum albuminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetLysosomal Pro-X carboxypeptidase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50328531(3-(Biphenyl-4-yl)-1-{2-[5-(3-fluorophenyl)-1H-imid...)
Affinity DataIC50: 79nMAssay Description:Inhibition of human PrCP by FRETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed