BDBM50328255 5-(2-chlorophenyl)-3-methyl-7-nitro-2,10-dihydrobenzo[e]pyrazolo[4,3-b][1,4]diazepine::CHEMBL1258821

SMILES Cc1n[nH]c2Nc3ccc(cc3C(=Nc12)c1ccccc1Cl)[N+]([O-])=O

InChI Key InChIKey=UVLBAPBHAHFJSY-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50328255   

TargetEpidermal growth factor receptor(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50328255(5-(2-chlorophenyl)-3-methyl-7-nitro-2,10-dihydrobe...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
LigandPNGBDBM50328255(5-(2-chlorophenyl)-3-methyl-7-nitro-2,10-dihydrobe...)
Affinity DataIC50: 35nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50328255(5-(2-chlorophenyl)-3-methyl-7-nitro-2,10-dihydrobe...)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of FAKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50328255(5-(2-chlorophenyl)-3-methyl-7-nitro-2,10-dihydrobe...)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50328255(5-(2-chlorophenyl)-3-methyl-7-nitro-2,10-dihydrobe...)
Affinity DataIC50: 72nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed