BDBM50328225 3-(4-(5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)thiazol-2-yl)piperazin-1-yl)benzamide::CHEMBL1258820

SMILES NC(=O)c1cccc(c1)N1CCN(CC1)c1ncc(s1)C(O)(C(F)(F)F)C(F)(F)F

InChI Key InChIKey=MKIUMXKJOUBICH-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50328225   

TargetMalonyl-CoA decarboxylase, mitochondrial(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50328225(3-(4-(5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human MCDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50328225(3-(4-(5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-...)
Affinity DataEC50:  1.40E+3nMAssay Description:Inhibition of MCD in mouse hepatocytes by whole cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed