BDBM50327999 CHEMBL1258351::N-(2-((5-cyanopyridin-2-yl)((1-methyl-1H-imidazol-5-yl)methyl)amino)ethyl)-N-(cyclohexylmethyl)pyridine-2-sulfonamide

SMILES Cn1cncc1CN(CCN(CC1CCCCC1)S(=O)(=O)c1ccccn1)c1ccc(cn1)C#N

InChI Key InChIKey=OAFSUCMIFLKJKF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50327999   

LigandPNGBDBM50327999(N-(2-((5-cyanopyridin-2-yl)((1-methyl-1H-imidazol-...)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of Rap1A geranylgeranylation expressed in mouse NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50327999(N-(2-((5-cyanopyridin-2-yl)((1-methyl-1H-imidazol-...)
Affinity DataIC50: 350nMAssay Description:Inhibition of human farnesyltransferase assessed as incorporation of [3H]FPP into H-Ras-CVLSMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50327999(N-(2-((5-cyanopyridin-2-yl)((1-methyl-1H-imidazol-...)
Affinity DataIC50: 288nMAssay Description:Inhibition of H-Ras farnesylation expressed in mouse NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50327999(N-(2-((5-cyanopyridin-2-yl)((1-methyl-1H-imidazol-...)
Affinity DataIC50: 690nMAssay Description:Inhibition of human geranylgeranyltransferase-1 assessed as incorporation of [3H]GGPP into H-Ras-CVLLMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed