BDBM50327986 CHEMBL1257770::N-(2-((4-cyanophenyl)((1-methyl-1H-imidazol-5-yl)methyl)amino)ethyl)-N-(furan-2-ylmethyl)-1-methyl-1H-imidazole-4-sulfonamide

SMILES Cn1cnc(c1)S(=O)(=O)N(CCN(Cc1cncn1C)c1ccc(cc1)C#N)Cc1ccco1

InChI Key InChIKey=IVBOJRZWKLEJOD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50327986   

LigandPNGBDBM50327986(N-(2-((4-cyanophenyl)((1-methyl-1H-imidazol-5-yl)m...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Rap1A geranylgeranylation expressed in mouse NIH3T3 cellsMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50327986(N-(2-((4-cyanophenyl)((1-methyl-1H-imidazol-5-yl)m...)
Affinity DataIC50: 870nMAssay Description:Inhibition of human farnesyltransferase assessed as incorporation of [3H]FPP into H-Ras-CVLSMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50327986(N-(2-((4-cyanophenyl)((1-methyl-1H-imidazol-5-yl)m...)
Affinity DataIC50: 1.34E+4nMAssay Description:Inhibition of human geranylgeranyltransferase-1 assessed as incorporation of [3H]GGPP into H-Ras-CVLLMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50327986(N-(2-((4-cyanophenyl)((1-methyl-1H-imidazol-5-yl)m...)
Affinity DataIC50: 800nMAssay Description:Inhibition of H-Ras farnesylation expressed in mouse NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed