BDBM50327981 1-methyl-1H-imidazole-4-sulfonic acid (2-bromoallyl)-{2-[(4-cyanophenyl)-(3-methyl-3H-imidazol-4-ylmethyl)amino]ethyl}-amide::CHEMBL215487::N-(2-bromoallyl)-N-(2-((4-cyanophenyl)((1-methyl-1H-imidazol-5-yl)methyl)amino)ethyl)-1-methyl-1H-imidazole-4-sulfonamide

SMILES Cn1cnc(c1)S(=O)(=O)N(CCN(Cc1cncn1C)c1ccc(cc1)C#N)CC(Br)=C

InChI Key InChIKey=SLBPKEUBXIAUGD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50327981   

LigandPNGBDBM50327981(1-methyl-1H-imidazole-4-sulfonic acid (2-bromoally...)
Affinity DataIC50: 180nMAssay Description:Inhibition of human farnesyltransferase assessed as incorporation of [3H]FPP into H-Ras-CVLSMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50327981(1-methyl-1H-imidazole-4-sulfonic acid (2-bromoally...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Rap1A geranylgeranylation expressed in mouse NIH3T3 cellsMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50327981(1-methyl-1H-imidazole-4-sulfonic acid (2-bromoally...)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of human geranylgeranyltransferase-1 assessed as incorporation of [3H]GGPP into H-Ras-CVLLMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50327981(1-methyl-1H-imidazole-4-sulfonic acid (2-bromoally...)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of H-Ras farnesylation expressed in mouse NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed