BDBM50327974 CHEMBL1258797::N-Benzyl,N-{2-[(4-Cyanophenyl)-(3-methyl-3H-imidazol-4-ylmethyl)-amino]-ethyl}Propane-1-sulfonamide

SMILES CCCS(=O)(=O)N(CCN(Cc1cncn1C)c1ccc(cc1)C#N)Cc1ccccc1

InChI Key InChIKey=KGKPSDXDDIJGRA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50327974   

LigandPNGBDBM50327974(N-Benzyl,N-{2-[(4-Cyanophenyl)-(3-methyl-3H-imidaz...)
Affinity DataIC50: 70nMAssay Description:Inhibition of H-Ras farnesylation expressed in mouse NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50327974(N-Benzyl,N-{2-[(4-Cyanophenyl)-(3-methyl-3H-imidaz...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Rap1A geranylgeranylation expressed in mouse NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50327974(N-Benzyl,N-{2-[(4-Cyanophenyl)-(3-methyl-3H-imidaz...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of human geranylgeranyltransferase-1 assessed as incorporation of [3H]GGPP into H-Ras-CVLLMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50327974(N-Benzyl,N-{2-[(4-Cyanophenyl)-(3-methyl-3H-imidaz...)
Affinity DataIC50: 48nMAssay Description:Inhibition of human farnesyltransferase assessed as incorporation of [3H]FPP into H-Ras-CVLSMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed