BDBM50327843 1-(4-Phenoxyphenyl)-3-(1-propionylpiperidin-4-yl)urea::CHEMBL1257879::US9296693, 16

SMILES CCC(=O)N1CCC(CC1)NC(=O)Nc1ccc(Oc2ccccc2)cc1

InChI Key InChIKey=SENALBWTNSROLJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50327843   

TargetBifunctional epoxide hydrolase 2(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM50327843(1-(4-Phenoxyphenyl)-3-(1-propionylpiperidin-4-yl)u...)
Affinity DataIC50: 3.5nMpH: 7.0Assay Description:IC50 values were determined using a sensitive fluorescent based assay (Anal. Biochem. 2005, 343, 66-75). Cyano(2-methoxynaphthalen-6-yl)methyl trans-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBifunctional epoxide hydrolase 2(Mouse)
The Regents of The University of California

US Patent
LigandPNGBDBM50327843(1-(4-Phenoxyphenyl)-3-(1-propionylpiperidin-4-yl)u...)
Affinity DataIC50: 0.400nMpH: 7.0Assay Description:IC50 values were determined using a sensitive fluorescent based assay (Anal. Biochem. 2005, 343, 66-75). Cyano(2-methoxynaphthalen-6-yl)methyl trans-...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBifunctional epoxide hydrolase 2(Mouse)
The Regents of The University of California

US Patent
LigandPNGBDBM50327843(1-(4-Phenoxyphenyl)-3-(1-propionylpiperidin-4-yl)u...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of mouse recombinant soluble epoxide hydrolase by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM50327843(1-(4-Phenoxyphenyl)-3-(1-propionylpiperidin-4-yl)u...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed