BDBM50327653 6,7-Dihydroxy-4-phenylcoumarin::CHEMBL1255818

SMILES Oc1cc2oc(=O)cc(-c3ccccc3)c2cc1O

InChI Key InChIKey=TZRNJQYCOSMOJS-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50327653   

TargetAldo-keto reductase family 1 member B1(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50327653(6,7-Dihydroxy-4-phenylcoumarin | CHEMBL1255818)
Affinity DataIC50: 6.63E+4nMAssay Description:Inhibition human recombinant aldose reductase 1 by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetSorbitol dehydrogenase(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50327653(6,7-Dihydroxy-4-phenylcoumarin | CHEMBL1255818)
Affinity DataIC50: 2.88E+5nMAssay Description:Inhibition sorbitol dehydrogenase by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Dalian University of Technology

Curated by ChEMBL
LigandPNGBDBM50327653(6,7-Dihydroxy-4-phenylcoumarin | CHEMBL1255818)
Affinity DataIC50: 3.27E+3nMAssay Description:Displacement of FAM-Bid peptide from recombinant N-terminal His6x-tagged human Mcl-1 expressed in Escherichia coli BL21 (DE3) incubated for 30 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Dalian University of Technology

Curated by ChEMBL
LigandPNGBDBM50327653(6,7-Dihydroxy-4-phenylcoumarin | CHEMBL1255818)
Affinity DataKi:  650nMAssay Description:Displacement of FAM-Bid peptide from recombinant N-terminal His6x-tagged human Mcl-1 expressed in Escherichia coli BL21 (DE3) incubated for 30 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed