BDBM50327540 3-((4-bromophenethylamino)methyl)-2-(thiophen-3-yl)quinolin-6-ol::CHEMBL1257612

SMILES Oc1ccc2nc(-c3ccsc3)c(CNCCc3ccc(Br)cc3)cc2c1

InChI Key InChIKey=SBOYUHNUCGIHSQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50327540   

TargetG-protein coupled bile acid receptor 1(Human)
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50327540(3-((4-bromophenethylamino)methyl)-2-(thiophen-3-yl...)
Affinity DataIC50: 82nMAssay Description:Agonist activity at human TGR5 receptor expressed in HEK293 cells assessed as intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50327540(3-((4-bromophenethylamino)methyl)-2-(thiophen-3-yl...)
Affinity DataIC50: 1.60E+3nMAssay Description:Agonist activity at mouse TGR5 receptor expressed in HEK293 cells assessed as intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed