BDBM50327493 8-(1-isopropylpiperidin-4-yloxy)-2-(2-methoxyethyl)-3,4-dihydropyrazino[1,2-a]indol-1(2H)-one::CHEMBL1257608

SMILES COCCN1CCn2c(cc3cc(OC4CCN(CC4)C(C)C)ccc23)C1=O

InChI Key InChIKey=IPFHLWSNKYSNJW-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50327493   

TargetHistamine H3 receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50327493(8-(1-isopropylpiperidin-4-yloxy)-2-(2-methoxyethyl...)
Affinity DataEC50:  51nMAssay Description:Inverse agonist activity at human recombinant histamine H3 receptor assessed as effect on [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50327493(8-(1-isopropylpiperidin-4-yloxy)-2-(2-methoxyethyl...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]-RAMH from human histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed