BDBM50327492 8-(3-(piperidin-1-yl)propoxy)-3,4-dihydropyrazino[1,2-a]indol-1(2H)-one::CHEMBL1258193

SMILES O=C1NCCn2c1cc1cc(OCCCN3CCCCC3)ccc21

InChI Key InChIKey=DDZUOFCXBAZBJH-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50327492   

TargetHistamine H3 receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50327492(8-(3-(piperidin-1-yl)propoxy)-3,4-dihydropyrazino[...)
Affinity DataEC50:  74nMAssay Description:Inverse agonist activity at human recombinant histamine H3 receptor assessed as effect on [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50327492(8-(3-(piperidin-1-yl)propoxy)-3,4-dihydropyrazino[...)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]-RAMH from human histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed