BDBM50326163 (E)-8-{2-[4-(2-Carboxyvinyl)phenyl]thiazol-4-yl}dibenzo[b,d]furan-4-carboxylic acid::CHEMBL1242827

SMILES OC(=O)\C=C\c1ccc(cc1)-c1nc(cs1)-c1ccc2oc3c(cccc3c2c1)C(O)=O

InChI Key InChIKey=KHXPSOZDSPHWJF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50326163   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326163((E)-8-{2-[4-(2-Carboxyvinyl)phenyl]thiazol-4-yl}di...)
Affinity DataIC50: 620nMAssay Description:Inhibition of human recombinant PTP1B after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326163((E)-8-{2-[4-(2-Carboxyvinyl)phenyl]thiazol-4-yl}di...)
Affinity DataIC50: 983nMAssay Description:Inhibition of human recombinant TCPTP after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326163((E)-8-{2-[4-(2-Carboxyvinyl)phenyl]thiazol-4-yl}di...)
Affinity DataIC50: 1.98E+3nMAssay Description:Inhibition of human recombinant LAR after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326163((E)-8-{2-[4-(2-Carboxyvinyl)phenyl]thiazol-4-yl}di...)
Affinity DataIC50: 620nMAssay Description:Inhibition of human recombinant PTP1B assessed as inhibition of hydrolysis of p-nitrophenol after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed