BDBM50326052 (E)-2-benzylidene-3-(cyclohexylamino)-2,3-dihydro-1H-inden-1-one::CHEMBL1241589

SMILES O=C1\C(=C\c2ccccc2)C(NC2CCCCC2)c2ccccc12

InChI Key InChIKey=XJDKPLZUXCIMIS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50326052   

TargetDual specificity protein phosphatase 1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50326052((E)-2-benzylidene-3-(cyclohexylamino)-2,3-dihydro-...)
Affinity DataIC50: 1.15E+4nMAssay Description:Inhibition of Myc-tagged human Dusp1 expressed in TPA-induced human HeLa cells assessed as decrease in dephosphorylation of pERK measured by immunost...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 6(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50326052((E)-2-benzylidene-3-(cyclohexylamino)-2,3-dihydro-...)
Affinity DataIC50: 1.23E+4nMAssay Description:Inhibition of Myc-tagged human Dusp6 expressed in TPA-induced human HeLa cells assessed as decrease in dephosphorylation of pERK measured by immunost...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed