BDBM50325718 2-(1-(4-chlorobenzyl)-1H-imidazol-2-yl)-N-(4-(trifluoromethyl)phenyl)pyrrolidine-1-carboxamide::CHEMBL1224118

SMILES FC(F)(F)c1ccc(NC(=O)N2CCCC2c2nccn2Cc2ccc(Cl)cc2)cc1

InChI Key InChIKey=LIYROGPUOXOGKP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50325718   

TargetC-C chemokine receptor type 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50325718(2-(1-(4-chlorobenzyl)-1H-imidazol-2-yl)-N-(4-(trif...)
Affinity DataIC50: 65nMAssay Description:Displacement of [125I]-MIP1-alpha from human recombinant CCR1 expressed in HEK293 cells after 4 hrs by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50325718(2-(1-(4-chlorobenzyl)-1H-imidazol-2-yl)-N-(4-(trif...)
Affinity DataIC50: 16nMAssay Description:Antagonist activity at CCR1 in human THP1 cells assessed as inhibition of CCL3-induced chemotaxis after 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed