BDBM50325108 CHEMBL1223381::N-(3-chloro-4-(N-(2-chlorophenyl)sulfamoyl)phenyl)picolinamide

SMILES Clc1ccccc1NS(=O)(=O)c1ccc(NC(=O)c2ccccn2)cc1Cl

InChI Key InChIKey=IXHCGJXBIHHIEF-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50325108   

TargetMetabotropic glutamate receptor 4(Human)
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50325108(N-(3-chloro-4-(N-(2-chlorophenyl)sulfamoyl)phenyl)...)
Affinity DataEC50:  20nMAssay Description:Positive allosteric modulator activity at human mGlu4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50325108(N-(3-chloro-4-(N-(2-chlorophenyl)sulfamoyl)phenyl)...)
Affinity DataEC50:  20nMAssay Description:Positive allosteric modulation of human mGlu4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2017
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50325108(N-(3-chloro-4-(N-(2-chlorophenyl)sulfamoyl)phenyl)...)
Affinity DataEC50:  19.8nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in CHO cells assessed as potentiation of glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50325108(N-(3-chloro-4-(N-(2-chlorophenyl)sulfamoyl)phenyl)...)
Affinity DataEC50:  20nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in BHK cells assessed as potentiation of glutamate-induced calcium mobilization afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed