BDBM50324811 (S)-2-(5,7-dichloro-2-(3-chlorobenzoyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(thiophene-2-carboxamido)propanoic acid::CHEMBL1222021

SMILES OC(=O)[C@H](CNC(=O)c1cccs1)NC(=O)c1c(Cl)cc2CN(CCc2c1Cl)C(=O)c1cccc(Cl)c1

InChI Key InChIKey=PBWGNAKIFNSLLR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50324811   

TargetIntegrin beta-2/Intercellular adhesion molecule 1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50324811((S)-2-(5,7-dichloro-2-(3-chlorobenzoyl)-1,2,3,4-te...)
Affinity DataIC50: 66nMAssay Description:Inhibition of LFA1/ICAM1 interaction in human Hut-78 cells by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50324811((S)-2-(5,7-dichloro-2-(3-chlorobenzoyl)-1,2,3,4-te...)
Affinity DataIC50: 240nMAssay Description:Inhibition of LFA1-mediated Staphylococcal enterotoxin B-stimulated human T cell activation in presence of 10% fetal bovine serumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed