BDBM50324345 CHEMBL1215361::Cyclohexyl-(4-difluoromethyl-6-piperazin-1-yl[2,4']bipyridinyl-2'-yl)amine

SMILES FC(F)c1cc(nc(c1)-c1ccnc(NC2CCCCC2)c1)N1CCNCC1

InChI Key InChIKey=VAVGLCQDZFLPHS-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50324345   

TargetSerine/threonine-protein kinase D1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324345(Cyclohexyl-(4-difluoromethyl-6-piperazin-1-yl[2,4'...)
Affinity DataEC50:  568nMAssay Description:Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear exportMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase D1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324345(Cyclohexyl-(4-difluoromethyl-6-piperazin-1-yl[2,4'...)
Affinity DataIC50: 17nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetPolycystin-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324345(Cyclohexyl-(4-difluoromethyl-6-piperazin-1-yl[2,4'...)
Affinity DataIC50: 76nMAssay Description:Inhibition of PKD2 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed