BDBM50324331 2'-Cyclohexylamino-6-piperazin-1-yl[2,4']bipyridinyl-4-carbonitrile::CHEMBL1215078

SMILES N#Cc1cc(nc(c1)-c1ccnc(NC2CCCCC2)c1)N1CCNCC1

InChI Key InChIKey=VJHWVSYYFZRUEK-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50324331   

TargetSerine/threonine-protein kinase D1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324331(2'-Cyclohexylamino-6-piperazin-1-yl[2,4']bipyridin...)
Affinity DataIC50: 18nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase D1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324331(2'-Cyclohexylamino-6-piperazin-1-yl[2,4']bipyridin...)
Affinity DataEC50:  66nMAssay Description:Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear exportMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetPolycystin-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324331(2'-Cyclohexylamino-6-piperazin-1-yl[2,4']bipyridin...)
Affinity DataIC50: 130nMAssay Description:Inhibition of PKD2 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed