BDBM50324271 (Z)-Ethyl 3-(4-Oxo-2-{[2-oxo-5-(phenylsulfonamido)indolin-3-ylidene]methyl}-4,5,6,7-tetrahydro-1H-indol-3-yl)propanoate::CHEMBL1215218

SMILES CCOC(=O)CCc1c(C=C2C(=O)Nc3ccc(NS(=O)(=O)c4ccccc4)cc23)[nH]c2CCCC(=O)c12

InChI Key InChIKey=BBTDOQATPTVBOJ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50324271   

TargetAurora kinase B(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324271((Z)-Ethyl 3-(4-Oxo-2-{[2-oxo-5-(phenylsulfonamido)...)
Affinity DataIC50: 214nMAssay Description:Inhibition of recombinant aurora BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324271((Z)-Ethyl 3-(4-Oxo-2-{[2-oxo-5-(phenylsulfonamido)...)
Affinity DataIC50: 84nMAssay Description:Inhibition of recombinant aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324271((Z)-Ethyl 3-(4-Oxo-2-{[2-oxo-5-(phenylsulfonamido)...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of c-Kit by radiometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324271((Z)-Ethyl 3-(4-Oxo-2-{[2-oxo-5-(phenylsulfonamido)...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PDGFRbeta by radiometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324271((Z)-Ethyl 3-(4-Oxo-2-{[2-oxo-5-(phenylsulfonamido)...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CSF1R by radiometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed