BDBM50324267 (Z)-3-(2-{[5-(Indolin-1-ylsulfonyl)-2-oxoindolin-3-ylidene]-methyl}-4-oxo-4,5,6,7-tetrahydro-1H-indol-3-yl)propanoic Acid::CHEMBL1215146

SMILES OC(=O)CCc1c(C=C2C(=O)Nc3ccc(cc23)S(=O)(=O)N2CCc3ccccc23)[nH]c2CCCC(=O)c12

InChI Key InChIKey=NROKZPYRSOKBHT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50324267   

TargetAurora kinase B(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324267((Z)-3-(2-{[5-(Indolin-1-ylsulfonyl)-2-oxoindolin-3...)
Affinity DataIC50: 292nMAssay Description:Inhibition of recombinant aurora BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324267((Z)-3-(2-{[5-(Indolin-1-ylsulfonyl)-2-oxoindolin-3...)
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed