BDBM50323247 6-(4-(3-(dimethylamino)propoxy)-3-(trifluoromethyl)phenyl)-1-methyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile::CHEMBL1209086::US9115126, Reference imidazopyridine derivative from WO 2009/010491 - Example 2a
SMILES CN(C)CCCOc1ccc(cc1C(F)(F)F)-c1cc2n(C)cnc2c(n1)C#N
InChI Key InChIKey=CZLJABZJYZVKFX-UHFFFAOYSA-N
Data 11 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50323247
Affinity DataIC50: 32nMAssay Description:The inhibitory activity of the compounds of the invention was demonstrated in vitro by measuring the inhibition of recombinant human Cathepsin S as f...More data for this Ligand-Target Pair
Affinity DataIC50: 84nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as accumulation of lip10 by Western blot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Inhibition of mouse cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 84nMAssay Description:Inhibition of cathepsin S-mediated proteolytic cleavage of MHC2 associated invariant chain in human JY cells assessed as accumulation of lip10 by Wes...More data for this Ligand-Target Pair
Affinity DataIC50: 776nMAssay Description:Inhibition of human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human cathepsin VMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
Affinity DataIC50: 776nMAssay Description:Inhibition of human cathepsin KMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human cathepsin BMore data for this Ligand-Target Pair