BDBM50322939 2-(3-chloro-4-fluorophenyl)-N-(3,4-difluorophenyl)-1-oxo-3-(pyridin-2-yl)-2,7-diazaspiro[3.5]nonane-7-carboxamide::CHEMBL1210628

SMILES Fc1ccc(NC(=O)N2CCC3(CC2)C(N(C3=O)c2ccc(F)c(Cl)c2)c2ccccn2)cc1F

InChI Key InChIKey=SBCYWFZLMMMDKJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50322939   

TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50322939(2-(3-chloro-4-fluorophenyl)-N-(3,4-difluorophenyl)...)
Affinity DataIC50: 41nMAssay Description:Inhibition of human CaV3.2 expressed in HEK293 cells at -100 mV membrane potential by Ionworks HT assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50322939(2-(3-chloro-4-fluorophenyl)-N-(3,4-difluorophenyl)...)
Affinity DataIC50: 41nMAssay Description:Inhibition of human CaV3.2 expressed in HEK293 cells at -100 mV membrane potential by Ionworks HT assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50322939(2-(3-chloro-4-fluorophenyl)-N-(3,4-difluorophenyl)...)
Affinity DataIC50: 1.77E+4nMAssay Description:Inhibition of human CaV3.2 expressed in HEK293 cells at -100 mV membrane potential by whole cell path clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed