BDBM50322870 (R)-3-(4-fluorophenyl)-N-((R)-6-(3-(pyrrolidin-1-yl)prop-1-en-2-yl)-1,2,3,4-tetrahydronaphthalen-1-yl)-3-(3-(trifluoromethyl)phenylsulfonamido)propanamide::CHEMBL1210756

SMILES Fc1ccc(cc1)[C@@H](CC(=O)N[C@@H]1CCCc2cc(ccc12)C(=C)CN1CCCC1)NS(=O)(=O)c1cccc(c1)C(F)(F)F

InChI Key InChIKey=UVRGUULEKWIGHV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50322870   

TargetB1 bradykinin receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50322870((R)-3-(4-fluorophenyl)-N-((R)-6-(3-(pyrrolidin-1-y...)
Affinity DataIC50: 1.30nMAssay Description:Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed