BDBM50322868 (R)-N-((R)-6-(3-(cyclobutylamino)prop-1-en-2-yl)-1,2,3,4-tetrahydronaphthalen-1-yl)-3-phenyl-3-(3-(trifluoromethyl)phenylsulfonamido)propanamide::CHEMBL1210754

SMILES FC(F)(F)c1cccc(c1)S(=O)(=O)N[C@H](CC(=O)N[C@@H]1CCCc2cc(ccc12)C(=C)CNC1CCC1)c1ccccc1

InChI Key InChIKey=MNVHGPUKRNXZDQ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50322868   

TargetB1 bradykinin receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50322868((R)-N-((R)-6-(3-(cyclobutylamino)prop-1-en-2-yl)-1...)
Affinity DataIC50: 44nMAssay Description:Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50322868((R)-N-((R)-6-(3-(cyclobutylamino)prop-1-en-2-yl)-1...)
Affinity DataKi:  3.40nMAssay Description:Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed