BDBM50322860 (R)-N-((R)-6-(3-((R)-3-hydroxypyrrolidin-1-yl)prop-1-en-2-yl)-1,2,3,4-tetrahydronaphthalen-1-yl)-3-phenyl-3-(3-(trifluoromethyl)phenylsulfonamido)propanamide::CHEMBL1210746

SMILES O[C@@H]1CCN(CC(=C)c2ccc3[C@@H](CCCc3c2)NC(=O)C[C@@H](NS(=O)(=O)c2cccc(c2)C(F)(F)F)c2ccccc2)C1

InChI Key InChIKey=SUTWITAROAZMMF-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50322860   

TargetB1 bradykinin receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50322860((R)-N-((R)-6-(3-((R)-3-hydroxypyrrolidin-1-yl)prop...)
Affinity DataIC50: 15nMAssay Description:Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50322860((R)-N-((R)-6-(3-((R)-3-hydroxypyrrolidin-1-yl)prop...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed