BDBM50322276 CHEMBL1172870::rac-1-Butyl-3-(cyclohexylmethyl)-9-[(2-phenyl-1,3-thiazol-4-yl)methyl]-1,4,9-triazaspiro[5.5]undecane-2,5-dionehydrochloride

SMILES CCCCN1C(=O)C(CC2CCCCC2)NC(=O)C11CCN(Cc2csc(n2)-c2ccccc2)CC1

InChI Key InChIKey=UVHALJBNIXPOQC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50322276   

TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322276(rac-1-Butyl-3-(cyclohexylmethyl)-9-[(2-phenyl-1,3-...)
Affinity DataIC50: 570nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed