BDBM50322269 CHEMBL1173707::rac-Ethyl 4-[1-butyl-3-(cyclohexylmethyl)-2,5-dioxo-1,4,9-triazaspiro[5.5]undec-9-yl]benzoate hydrochloride

SMILES CCCCN1C(=O)C(CC2CCCCC2)NC(=O)C11CCN(CC1)c1ccc(cc1)C(=O)OCC

InChI Key InChIKey=JIFAMUYNXPIZSI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50322269   

TargetC-C chemokine receptor type 5(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50322269(rac-Ethyl 4-[1-butyl-3-(cyclohexylmethyl)-2,5-diox...)
Affinity DataIC50: 3.00E+3nMAssay Description:Antagonist activity at human CCR5 receptor expressed in CHO cells assessed as inhibition of MIP-1-alpha-stmulated calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed