BDBM50322033 2-Methylisoindole-1,3-dione-5-yl 3-(6-aminopyridin-3-yl)propionate::CHEMBL1171655

SMILES CN1C(=O)c2ccc(OC(=O)CCc3ccc(N)nc3)cc2C1=O

InChI Key InChIKey=OSPQCZJJZMQHLM-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50322033   

TargetTryptase beta-2/delta/gamma(Human)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50322033(2-Methylisoindole-1,3-dione-5-yl 3-(6-aminopyridin...)
Affinity DataIC50: 190nMAssay Description:Inhibition of tryptase (unknown origin) using t-Boc-Phe-Ser-Arg-MCA as substrate after 5 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50322033(2-Methylisoindole-1,3-dione-5-yl 3-(6-aminopyridin...)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of thrombin (unknown origin) using t-Boc-Val-Pro-Arg-MCA as substrate after 5 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrypsin(Human)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50322033(2-Methylisoindole-1,3-dione-5-yl 3-(6-aminopyridin...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of trypsin (unknown origin) using Bz-Arg-pNA.HCl as substrate after 5 mins by colorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Bovine)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50322033(2-Methylisoindole-1,3-dione-5-yl 3-(6-aminopyridin...)
Affinity DataKi:  7.00E+3nMAssay Description:Binding affinity to bovine thrombin after 3 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed